LANCÔME LAUNCHES THE REVOLUTIONARY ABSOLUE LONGEVITY MD RANGE

Lancôme consolidates its position as a leader in the scientific territory of longevity, placing longevity science at the heart of its innovation strategy. By orchestrating strategic collaborations with the world’s most advanced biotechnology firms, the brand redefines industry standards and champions a proactive, scientific vision of beauty that goes beyond the simple pursuit of a younger appearance, towards promoting the biological vitality of the skin. Today, Lancôme opens a new era of longevity in beauty through its partnership with Swiss biotechnology company Timeline®.

The Lancôme and Timeline® Partnership: a revolutionary innovation in cellular energy

In 2024, L’Oréal Group became the first player to place beauty at the heart of the global conversation on longevity, by investing in Timeline®, a Swiss biotechnology company pioneering longevity science. Today, Lancôme brings this partnership to the forefront of the consumer market. This collaboration focuses on Mitopure®, a proprietary molecule backed by over 50 million dollars in research and development investment and 15 years of research. Mitopure® is a highly pure form of Urolitin A, a postbiotic clinically proven to re-energise mitochondria the cell’s powerhouses through a cellular renewal process known as mitophagy. This partnership will lay the groundwork for a new Lancôme skincare range, combining Mitopure® with the brand’s proprietary compounds to deliver clinically proven longevity benefits for the skin. Each product is designed to act on the visible biological age of the skin, marking the first global-scale implementation of Mitopure® through a major beauty brand.

“For Lancôme, longevity is a frontier of radical progress, not a matter of appearance. We are defining a new scientific era in which beauty is proactive, decoding the fundamental biological mechanisms of skin ageing. By orchestrating meaningful partnerships with the world’s most advanced biotechnology innovators such as Timeline and its molecule Mitopure® we are accelerating our mission to deliver high-performance solutions. Our goal is to change the conversation about ageing, using cutting-edge science to restore cellular vitality and offer women a new perspective on their own skin trajectory,” said Vania Lacascade, Global President of the Lancôme brand.

“Collaborating with Lancôme marks an exciting new chapter for Timeline®, reinforcing our core belief in a multidimensional approach to redefining the way we age. This partnership represents a remarkable opportunity to democratise our longevity molecule, Mitopure®, making its advanced skin benefits more accessible than ever,” added Chris Rinsch, co-founder and President of Timeline®.

A bold ambition: leader in the territory of skin LONGEVITY for Lancôme

Skin longevity represents a major scientific breakthrough that opens a new social paradigm. It is no longer about masking the signs of time, but about decoding fundamental biological mechanisms to preserve and restore skin health. This leadership entails the responsibility to empower consumers with new knowledge and to set new standards for the category through an inclusive and optimistic vision of ageing.

A rapidly expanding longevity ecosystem

The launch of the Absolue Longevity MD range at the annual convention of the American Academy of Dermatology (AAD) in Denver, Colorado, from 27 to 29 March 2026, marks a key moment. The arrival of Timeline® within our Integrative Longevity Science ecosystem completes a progressive strategy already initiated by Lancôme.

Towards a new beauty paradigm

By combining state-of-the-art analysis, innovative active ingredients and the decoding of deep cellular processes, Lancôme is not merely launching products it is building a holistic, science- and data-driven approach to beauty longevity.

In this new paradigm, chronological age becomes just a number. The priority is the visible biological age of the skin the only one we can influence. Lancôme is not merely following the longevity movement; it is actively shaping it, transforming complex scientific discoveries into high-performance solutions.

DEMI MOORE AND ZOE SALDAÑA ARE LANCÔME’S NEW GLOBAL AMBASSADORS

The innovative vision of the range is embodied by three iconic figures Demi Moore, Zoe Saldaña and Ella McCutcheon who become the new global ambassadors of the Lancôme brand, uniting cutting-edge science with the power of two of Hollywood’s most remarkable personalities.

DEMI MOORE: THE POWER TO RESET YOUR STORY

An iconic presence in cinema, whose career spans five decades, Demi Moore has defined and redefined herself with fearless courage. Her resilience, boldness and determination make her the perfect embodiment of optimism, at any age.

“Lancôme represents beauty at every level, beyond the mere surface. It represents progress, the science of possibility and the belief that women deserve to feel beautiful and uplifted at every stage of life. Learning to accept yourself is a journey, and it is an honour for me to join a house that celebrates the same spirit. Beauty is an act of self-care, self-love and self-acceptance, and that is what I hope to embody in our partnership,” said Demi Moore.

In her first campaign for the brand, Demi Moore will be the face of the RESET protocol from the Absolue Longevity MD range.

ZOE SALDAÑA: AUTHENTICITY AND MODERN ELEGANCE

An Oscar-winning actress and one of the highest-grossing film stars of all time, Zoe Saldaña brings an authentic perspective and sophisticated elegance to the brand. Her presence reflects a modern femininity and a radiant confidence.

“For me, Lancôme has always represented a deeply human and grounded vision of beauty. This resonates with who I am as a woman, as an actress and as a mother. Beauty, for me, means conviction: the courage to set your own rules and the confidence to honour them,” said Zoe Saldaña.

In the launch campaign, Zoe Saldaña will be the face of the INTERCEPT protocol.

LANCÔME SETS A NEW STANDARD IN LONGEVITY SCIENCE, FORMULATING FOR THE FIRST TIME IN AN ADVANCED SKINCARE PRODUCT A PHYSICIAN-RECOMMENDED LONGEVITY SUPPLEMENT, UROLITIN-A.*

The new ABSOLUE LONGEVITY MD range is built on a major innovation: the world-first introduction into a skincare product of Mitopure™ (Urolitin-A), an active compound from a physician-recommended longevity supplement developed by Swiss biotechnology company Timeline.

Urolitin-A is recognised as a powerful rejuvenator of the cell’s “batteries” (mitochondria), acting directly at the root of the visible ageing process. As skin ages, mitochondrial efficiency declines. By stimulating the mitochondrial recycling process, Mitopure™ helps maintain skin performance over time, acting directly at the root of the visible ageing process.

This technology is the result of 15 years of research and investment of over 50 million dollars.

ABOUT TIMELINE®

Timeline (parent company Amazentis) is a Swiss company pioneering health sciences, dedicated to revolutionising the longevity industry with its innovative, clinically proven ingredient, Mitopure®. Offering a comprehensive approach to cellular health, Timeline incorporates the benefits of Mitopure into cutting-edge nutritional supplements and topical skin health products. With over a decade of expertise in ageing science research, Timeline aims to push the boundaries of human health, contributing to a future where everyone can live longer and healthier. The company is backed by over 15 years of research conducted by distinguished scientists, multiple clinical studies and over 50 global patents. Nestlé Health Science and L’Oréal are investors in the company. More information at www.timeline.com.

THREE INTERVENTION MODELS FOR EVERY STAGE OF LIFE

The Absolue Longevity MD range is designed as a personalised protocol, adapting to the skin’s needs according to its biological age, offering three precise intervention models:

1. ANTICIPATE (chronological age < 35) – advanced preventive care, young skin. Ambassador: Ella McCutcheon

• Objective: Acts on the signs of ageing before they become visible, protecting the skin’s youthful potential.
• Proven results: -16% forming fine lines¹, up to -50% of the skin’s oxidation process².

2. INTERCEPT (chronological age 35–55) – care for advanced revitalisation, visible signs. Ambassador: Zoe Saldaña

• Objective: Corrects signs of ageing as they appear.
• Proven results: +4 million new cells every day, +52% improvement in skin elasticity³, 3 types of wrinkles visibly reduced.

3. RESET (chronological age > 55) – care for advanced regeneration, mature skin. Ambassador: Demi Moore

• Objective: Reduces signs of ageing as soon as they appear.
• Proven results: – 4 years from the skin’s biological age⁴, +55% firmness and elasticity.

SUSTAINABLE DESIGN

The packaging of the Absolue Longevity MD range is a modern reinterpretation of the iconic Absolue design from 1965. The Intercept Cream is refillable, reflecting Lancôme’s commitment to longevity not only at the level of the skin, but also in the creation process.

Through the fusion of cutting-edge biology, precision technology and the power of exceptional ambassadors, Absolue Longevity MD gives every woman control over the visible ageing trajectory of her skin.

Notes:

• *Based on an IQVIA study, December 2025, in which 21 US physicians self-declared as longevity specialists.
• ¹ Clinical evaluation, 76 subjects, after 3 months of use
• ² Ex vivo test on skin surface oxidation using the new Anticipate cream
• ³ Instrumental test, 40 subjects
• ⁴ Instrumental test, 94 subjects after 2 months of use