After 25 years of pioneering research on skin mother cells, Dior Capture highlighted the importance of oxygen transport in skin regeneration in 2025. In collaboration with Knut Woltjen, Associate Professor at CiRA (Center for iPS Cell Research and Application) in Kyoto, Dior researchers were able to demonstrate that from the age of 25, cellular respiration slows down, leading to a decline in skin renewal.

This research led to the development of the signature Dior Capture technology: OX-C Treatment™, which targets an oxygen transporter at the heart of cells. By promoting the supply of oxygen, it stimulates skin regeneration and triples the production of collagen I. The skin is then firmer and visibly smoother.

To complete its iconic line, Dior has created a series of high-precision complementary skincare since 2024, offering powerful combinations of dermatological ingredients with remarkable results. These solutions target specific needs such as wrinkles, skin quality and a lifting effect for the eyes, with instant and long-term results validated by comprehensive protocols. Designed to give the Dior Capture serum a real boost, they offer additional action on specific problems.

In August 2026, Dior Capture reinvents Hyalushot in Hyalushot Advanced, for visible smoothing and plumping results. Inspired by the latest generations of regenerating PDRN injections, the line is enriched with the PDRN-Shot: a high-performance solution for intensely reviving radiance and reducing visible signs of fatigue.

PDRN-SHOT, THE NEW DIOR CAPTURE BOOSTER INSPIRED BY THE LATEST REGENERATING PDRN INJECTIONS

A study conducted by Dior research using a generative AI model identified 3 key dimensions of perceived skin fatigue as follows: a loss of vitality, color variations, and altered skin texture. These surface modifications can lead to a skin that is less smooth, reflects light less evenly, and is less radiant. Aging in the skin is thus accentuated even further.

The progressive decrease in mother cell activity also contributes to this loss of radiance. Less well anchored and more dispersed in the skin, mother cells can no longer fully perform their role of skin regeneration. The surface of the skin then becomes less even, which impairs uniform light reflection and decreases radiance.

To respond to these visible signs of skin fatigue and loss of radiance, Dior unveils a new solution: Dior Capture PDRN-Shot. Inspired by professional PDRN injections, it acts to regenerate skin tissues, reduce visible signs of fatigue and intensely revitalize radiance. A highly effective revitalizing shot for visibly younger skin.

PDRN, a key molecule involved in skin regeneration mechanisms

PDRN (or polydeoxyribonucleotide) is a DNA fragment and an active ingredient recognized for its highly regenerative properties. Used in the latest generation of aesthetic injections, it is currently among the most widely practiced treatments in aesthetic medicine in Asia. More recently, PDRN use has also been established in cosmetics, with the development of topical applications, often formulated from salmon DNA.

PDRN-Shot: a new generation, plant-derived PDRN combined with two reference actives for a tenfold action on skin regeneration and radiance.

For the PDRN-Shot, Dior innovated by choosing a phyto-PDRN: extracted from a fragment of rice DNA obtained by hydrolysis, it stands out for its small size and its effective action on the main skin regeneration mechanisms.

It demonstrates an intense effect on certain mechanisms, superior to that of salmon PDRN:
– Regenerative power: +65% i.e. 4.6x higher than salmon PDRN.
– The dermo-epidermal junction is reinforced: +214% (laminin 5) i.e. 6.2x higher than salmon PDRN. The skin is firmer and visibly smoother.
– The skin barrier is consolidated: +81% (occludin) i.e. 2x higher than salmon PDRN.

In addition, a pro-penetrating exo-liposome with patented double vectorization ensures 8 hours of continuous diffusion in the skin. Dior has proven that vectorized PDRN is more efficient than non-vectorized PDRN on the CD44 marker (key for hydration) present in the basal layer.

For the first time, Dior combines its PDRN with 2 reference dermatological ingredients:
– Vitamin Cg, which evens out the complexion, reduces the appearance of dark spots and revives the skin’s natural radiance.
– Niacinamide, which improves skin texture, refines the appearance of pores and visibly smooths the skin.

The effect of these 3 complementary actives is multiplied when they are combined, forming a comprehensive complex that promotes skin regeneration and restores a radiant complexion. To prove it, Dior demonstrated that in combination, they deliver a far superior performance: notably, they are 2x more effective on oxidized proteins compared to PDRN alone.

In addition, lily extract ensures optimal skin regeneration that is key to maintaining skin’s visible youthfulness.

In depth and on the surface, PDRN-Shot offers a complete solution allowing intense revitalization for skin that looks younger and less tired.

A formula with a firming and illuminating effect

The formula, which includes an oil with a tightening effect, visibly and immediately firms the face. Thanks to 100% natural refractive particles, the formula offers a healthy glow effect and instant universal radiance.

Visible high-performance validated by instrumental and clinical tests

From the first application, PDRN-Shot revives radiance in tired skin and offers increased results, day after day:
– Instantly, the skin is 25% more radiant for 8 hours.
– In 1 month, dark spots visibly reduced by 25%.
– In 1 shot, the skin is 65% smoother and 62% more radiant.

When combined with Dior Capture Le Sérum, the PDRN-Shot increases its performance, for skin that is 2x smoother, firmer and visibly more radiant.

HYALUSHOT ADVANCED, THE NEW EXPERT WRINKLE CORRECTOR

A key molecule for visibly youthful skin, hyaluronic acid helps maintain skin structure and volume, thus making it possible to deeply fill wrinkles. Although it is naturally present in the skin, it remains very fragile and temporary (half of the hyaluronic acid in the epidermis has a lifespan of no more than 3 hours), due to the following factors:
– It is continuously broken down by hyaluronidase, an enzyme that fragments it.
– It is subject to progressive migration from the epidermis to the dermis, linked to decreased mother cell anchoring, which accelerates natural deterioration.
– Lastly, production decreases sharply with age, reducing by as much as 75% over 30 years.

Consequently, wrinkles multiply, deepen and become more visible.

Advanced technology with optimal results

To compensate for this loss of hyaluronic acid, Dior Capture reinvents its expert corrector. Hyalushot Advanced is based on a patented complex: [Poly H.A] Technology, combining 3 forms of hyaluronic acid with complementary molecular weights to act at different levels of the skin:
– A macro form of hyaluronic acid: cross-linked and with a higher molecular weight, it provides increased resistance on the skin’s surface. It protects against moisture loss.
– A micro form of hyaluronic acid: with a lower molecular weight, it penetrates deeper into the epidermis, allowing targeted in-depth action.

This hyaluronic acid duo acts on collagen VII: boosted by 76%, it strengthens the dermo-epidermal junction, helping to limit hyaluronic acid leaks. The skin is firmer and visibly smoother.

– Lastly, Hyalushot Advanced incorporates pure hyaluronic acid: even smaller, it penetrates the deepest layers of the epidermis and acts on aquaporin-3, one of the essential markers ensuring water circulation at the heart of the skin.

2 new actives complete this technology:
– A peptide stimulates hyaluronic acid production, increasing it by 355% in the skin.
– A protective polysaccharide acting as a biological shield, inhibiting 44% of hyaluronidase activity an enzyme involved in the natural deterioration of hyaluronic acid in order to maintain an optimal supply and limit its deterioration.

Hyalushot Advanced offers a complete visible age-defying response: its active ingredients deliver hyaluronic acid to the skin, boost its production and protect it from deterioration. The 9 types of wrinkles are visibly corrected and filled, the skin is plumped and smoothed.

In addition, lily extract ensures optimal skin regeneration, which is key to maintaining visibly youthful skin.

A new texture with 3D fibers

From the moment of application, the formula equipped with 3D fibers, fills in hollows and visibly blurs wrinkles. Enriched with illuminating mother-of-pearl particles, the shadowy zones created by wrinkles are diminished, for visibly smoother and radiant skin.

Visible high-performance validated by instrumental and clinical tests

Hyalushot Advanced smooths the appearance of wrinkles instantly and visibly plumps established wrinkles, day after day:
– Wrinkle visibility is reduced: -30% in 2 hours.
– Visible age of established wrinkles is reduced by 3 years in 1 month.

The effectiveness of Hyalushot Advanced is measured on 9 types of facial wrinkles: Forehead wrinkles, frown lines, crow’s feet, under-eye wrinkles, cheek folds, bunny lines on the upper and lateral parts of the nose, nasolabial folds, lip lines, marionette lines at the lower corners of the mouth.

Used in combination with Dior Capture Le Sérum, it boosts the smooth appearance of the skin by 50%.